Transcriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting | Zendy

Vajdana Tomić | Zendy; Stefan Rußwurm | Zendy; E Möller | Zendy; Ralf A. Claus | Zendy; Markus Blaess | Zendy; Frank M. Brunkhorst | Zendy; Mathias Bruegel | Zendy; Kerstin Bode | Zendy; Frank Bloos | Zendy; Jens Wippermann | Zendy; T Wahlers | Zendy; HansPeter Deigner | Zendy; JeanClaude Thiéry | Zendy; Konrad Reinhart | Zendy; Michael Bauer | Zendy

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Transcriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting

Author(s) -

Vajdana Tomić,

Stefan Rußwurm,

E Möller,

Ralf A. Claus,

Markus Blaess,

Frank M. Brunkhorst,

Mathias Bruegel,

Kerstin Bode,

Frank Bloos,

Jens Wippermann,

T Wahlers,

HansPeter Deigner,

JeanClaude Thiéry,

Konrad Reinhart,

Michael Bauer

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.531152

Subject(s) - medicine , inflammation , cardiopulmonary bypass , monocyte , systemic inflammation , tumor necrosis factor alpha , transcriptome , immunology , receptor , gene expression , gene , biology , biochemistry

Coronary artery bypass grafting (CABG) using cardiopulmonary bypass (CPB) provides controlled operative conditions but induces a whole-body inflammatory response capable of initiating devastating morbidity and mortality. Although technically more demanding, deliberate avoidance of CPB in off-pump surgery attenuates the physiological insult associated with CABG.

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