Prevention of Left Ventricular Remodeling With Granulocyte Colony-Stimulating Factor After Acute Myocardial Infarction
Author(s) -
Hüseyin İnce,
Michael Petzsch,
Hans Dieter Kleine,
Heike Eckard,
Tim C. Rehders,
Detlev Burska,
Stephan Kische,
Mathias Freund,
Christoph Nienaber
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.524827
Subject(s) - medicine , myocardial infarction , cardiology , granulocyte colony stimulating factor , percutaneous coronary intervention , ejection fraction , mace , conventional pci , heart failure , chemotherapy
Experimental and clinical evidence has recently shown that pluripotent stem cells can be mobilized by granulocyte colony-stimulating factor (G-CSF) and may enhance myocardial regeneration early after primary percutaneous coronary intervention (PCI) management of acute myocardial infarction. Sustained or long-term effects of mobilized CD34-positive mononuclear stem cells, however, are unknown.
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