Aprotinin Decreases Postoperative Bleeding and Number of Transfusions in Patients on Clopidogrel Undergoing Coronary Artery Bypass Graft Surgery | Zendy

Jan van der Linden | Zendy; Gabriella Lindvall | Zendy; Ulrik Sartipy | Zendy

Open Access

Aprotinin Decreases Postoperative Bleeding and Number of Transfusions in Patients on Clopidogrel Undergoing Coronary Artery Bypass Graft Surgery

Author(s) -

Jan van der Linden,

Gabriella Lindvall,

Ulrik Sartipy

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.524611

Subject(s) - medicine , aprotinin , clopidogrel , anesthesia , perioperative , surgery , angina , artery , antifibrinolytic , coronary artery bypass surgery , unstable angina , cardiac surgery , platelet , aspirin , tranexamic acid , cardiology , myocardial infarction , blood loss

Clopidogrel, an irreversible platelet inhibitor, is used to treat patients with unstable angina. These patients often present for coronary artery bypass graft surgery (CABG) and are at increased risk for perioperative bleeding. The current investigation evaluates the impact of aprotinin on bleeding and transfusion requirements in clopidogrel-treated patients undergoing CABG.

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