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Elevated High-Density Lipoprotein Cholesterol Levels Are Protective Against Plaque Progression
Author(s) -
Stein Harald Johnsen,
Ellisiv B. Mathiesen,
Einar Fosse,
Oddmund Joakimsen,
Eva Stensland-Bugge,
Inger Njølstad,
Egil Arnesen
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.522706
Subject(s) - medicine , cholesterol , vulnerable plaque , high density lipoprotein , lipoprotein , ldl cholesterol , cardiology , endocrinology
There is an inverse relationship between HDL cholesterol and coronary heart disease. Experimental studies have indicated that HDL cholesterol may exert an antiatherogenic effect by inducing regression of atherosclerotic plaques and by turning lipid-rich plaques into more fibrotic lesions. In this prospective, population-based ultrasound study, we investigated how HDL cholesterol relates to carotid plaque progression.

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