Sudden Unexplained Death | Zendy

Hanno L. Tan | Zendy; Nynke Hofman | Zendy; Irene M. van Langen | Zendy; Allard C. van der Wal | Zendy; Arthur A.M. Wilde | Zendy

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Sudden Unexplained Death

Author(s) -

Hanno L. Tan,

Nynke Hofman,

Irene M. van Langen,

Allard C. van der Wal,

Arthur A.M. Wilde

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.522581

Subject(s) - catecholaminergic polymorphic ventricular tachycardia , medicine , brugada syndrome , sudden death , hypertrophic cardiomyopathy , sudden cardiac death , family history , long qt syndrome , cardiomyopathy , disease , heart disease , genetic testing , ventricular tachycardia , cardiology , pediatrics , qt interval , heart failure , ryanodine receptor 2 , ryanodine receptor , calcium

Sudden death mostly follows from cardiac disorders that elicit lethal ventricular arrhythmias. In young individuals, it often remains unexplained because history and/or postmortem analysis are absent or provide no clue. Because such sudden unexplained deaths (SUDs) may have heritable causes, cardiological and genetic assessment of surviving relatives of SUD victims may reveal the underlying disease and unmask presymptomatic carriers. We aimed to establish the diagnostic yield of such assessments.

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