Chronic Thrombus Detection With In Vivo Magnetic Resonance Imaging and a Fibrin-Targeted Contrast Agent | Zendy

Marc Sirol | Zendy; Valentı́n Fuster | Zendy; Juan J. Badimon | Zendy; John T. Fallon | Zendy; JeanFrançois Toussaint | Zendy; Zahi A. Fayad | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Chronic Thrombus Detection With In Vivo Magnetic Resonance Imaging and a Fibrin-Targeted Contrast Agent

Author(s) -

Marc Sirol,

Valentı́n Fuster,

Juan J. Badimon,

John T. Fallon,

JeanFrançois Toussaint,

Zahi A. Fayad

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.522110

Subject(s) - thrombus , medicine , fibrin , magnetic resonance imaging , thrombosis , in vivo , radiology , histopathology , pathology , cardiology , microbiology and biotechnology , biology , immunology

Arterial thrombosis plays a critical role in acute coronary syndromes and stroke. Therefore, the ability to detect thrombus in vivo has a significant clinical implication. Magnetic resonance imaging (MRI) has shown promise in noninvasive thrombus detection. However, thrombus characterization and age definition remain difficult. We sought to evaluate the use of a fibrin-targeted peptide (EP-2104R) for MR thrombus detection and to compare this modality with non-contrast-enhanced (NCE) MRI and with Gd-DTPA injection at various ages and time points after thrombus generation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research