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Characterization of Atherosclerotic Plaques by Laser Speckle Imaging
Author(s) -
Seemantini K. Nadkarni,
Brett E. Bouma,
Tina Helg,
Raymond C. K. Chan,
Elkan F. Halpern,
Alexandra H. Chau,
Milan Singh Minsky,
Jason T. Motz,
Stuart L. Houser,
Guillermo J. Tearney
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.520098
Subject(s) - speckle pattern , decorrelation , viscoelasticity , medicine , optics , biomedical engineering , nuclear medicine , materials science , physics , mathematics , algorithm , composite material
A method capable of determining atherosclerotic plaque composition and measuring plaque viscoelasticity can provide valuable insight into intrinsic features associated with plaque rupture and can enable the identification of high-risk lesions. In this article, we describe a new optical technique, laser speckle imaging (LSI), that measures an index of plaque viscoelasticity. We evaluate the potential of LSI for characterizing atherosclerotic plaque.

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