Changes in Ventricular Size and Function in Patients Treated With Valsartan, Captopril, or Both After Myocardial Infarction | Zendy

Scott D. Solomon | Zendy; Hicham Skali | Zendy; Nagesh S. Anavekar | Zendy; Mikhail Bourgoun | Zendy; Ståle Barvik | Zendy; Jalal K. Ghali | Zendy; J. Wayne Warnica | Zendy; Margarita Khrakovskaya | Zendy; J. Malcolm O. Arnold | Zendy; Yuri G. Schwartz | Zendy; Eric J. Velazquez | Zendy; Robert M. Califf | Zendy; John J.V. McMurray | Zendy; Marc A. Pfeffer | Zendy

Open Access

Changes in Ventricular Size and Function in Patients Treated With Valsartan, Captopril, or Both After Myocardial Infarction

Author(s) -

Scott D. Solomon,

Hicham Skali,

Nagesh S. Anavekar,

Mikhail Bourgoun,

Ståle Barvik,

Jalal K. Ghali,

J. Wayne Warnica,

Margarita Khrakovskaya,

J. Malcolm O. Arnold,

Yuri G. Schwartz,

Eric J. Velazquez,

Robert M. Califf,

John J.V. McMurray,

Marc A. Pfeffer

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.508093

Subject(s) - captopril , valsartan , medicine , ejection fraction , myocardial infarction , cardiology , heart failure , ventricular remodeling , blood pressure

Angiotensin-converting enzyme (ACE) inhibitors have been shown to attenuate left ventricular (LV) enlargement in association with reducing mortality after myocardial infarction (MI). Preclinical data suggest that angiotensin receptor blockers (ARBs) may have similar structural and functional effects after MI. The Valsartan in Acute Myocardial Infarction (VALIANT) Echo study was designed to test the hypothesis that the ARB valsartan, either alone or in combination with captopril, could attenuate progressive LV enlargement or improve LV ejection fraction to a greater extent than captopril alone.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research