Human Atrial Ion Channel and Transporter Subunit Gene-Expression Remodeling Associated With Valvular Heart Disease and Atrial Fibrillation | Zendy

Nathalie Gaborit | Zendy; Marja Steenman | Zendy; Guillaume Lamirault | Zendy; Nolwenn Le Meur | Zendy; Sabrina Le Bouter | Zendy; Gilles Lande | Zendy; Jean Léger | Zendy; Flavien Charpentier | Zendy; Torsten Christ | Zendy; Dobromir Dobrev | Zendy; Denis Escande | Zendy; Stanley Nattel | Zendy; Sophie Demolombe | Zendy

Open Access

Human Atrial Ion Channel and Transporter Subunit Gene-Expression Remodeling Associated With Valvular Heart Disease and Atrial Fibrillation

Author(s) -

Nathalie Gaborit,

Marja Steenman,

Guillaume Lamirault,

Nolwenn Le Meur,

Sabrina Le Bouter,

Gilles Lande,

Jean Léger,

Flavien Charpentier,

Torsten Christ,

Dobromir Dobrev,

Denis Escande,

Stanley Nattel,

Sophie Demolombe

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.506857

Subject(s) - atrial fibrillation , medicine , sinus rhythm , valvular heart disease , ion channel , phospholamban , atrium (architecture) , potassium channel , cardiology , endocrinology , heart failure , receptor

Valvular heart disease (VHD), which often leads to atrial fibrillation (AF), and AF both cause ion-channel remodeling. We evaluated the ion-channel gene expression profile of VHD patients, in permanent AF (AF-VHD) or in sinus rhythm (SR-VHD), in comparison with patients without AF or VHD, respectively.

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