Synergistic Neovascularization by Mixed Transplantation of Early Endothelial Progenitor Cells and Late Outgrowth Endothelial Cells
Author(s) -
ChangHwan Yoon,
Jin Hur,
Kyung Woo Park,
Ji-Hyun Kim,
Choon-Soo Lee,
IlYoung Oh,
Tae Youn Kim,
Hyun-Jai Cho,
HyunJae Kang,
InHo Chae,
HanKwang Yang,
ByungHee Oh,
Young-Bae Park,
Hyo-Soo Kim
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.503433
Subject(s) - progenitor cell , matrigel , neovascularization , angiogenesis , microbiology and biotechnology , transplantation , endothelial stem cell , stem cell , cd34 , medicine , immunology , cancer research , biology , in vitro , biochemistry
Two types of cells are cultured from the human peripheral blood, early endothelial progenitor cells (EPCs) and outgrowth endothelial cells (OECs), as previously reported. Here, we further characterize these cells, especially with respect to their different origins and functions both in vitro and in vivo. We also investigated whether the combination of these different cell types shows synergism during neovascularization.
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