Altered Dynamics of Action Potential Restitution and Alternans in Humans With Structural Heart Disease
Author(s) -
Marcus L. Koller,
S. K. G. Maier,
Anna R. Gelzer,
Wolfgang R. Bauer,
Malte Meesmann,
Robert F. Gilmour
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.502831
Subject(s) - restitution , cardiology , medicine , diastole , ventricular tachycardia , heart disease , blood pressure , political science , law
Restitution kinetics and alternans of ventricular action potential duration (APD) have been shown to be important determinants of cardiac electrical stability. In this study, we tested the hypothesis that APD restitution and alternans properties differ between normal and diseased human ventricular myocardium.
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