Transendocardial Autologous Bone Marrow Mononuclear Cell Injection in Ischemic Heart Failure | Zendy

Hans Fernando Rocha Dohmann | Zendy; Emerson C. Perin | Zendy; Christina Maeda Takiya | Zendy; Guilherme V. Silva | Zendy; Suzana A. Silva | Zendy; A Sousa | Zendy; Cláudio Tinoco Mesquita | Zendy; Maria-Isabel D. Rossi | Zendy; Bernardo M.O. Pascarelli | Zendy; Isabella Mariana de Assis | Zendy; Hélio S. Dutra | Zendy; João A.R. Assad | Zendy; Rodrigo V. Castello-Branco | Zendy; Cantidio Drummond | Zendy; Hans J.F. Dohmann | Zendy; James T. Willerson | Zendy; Radovan Borojević | Zendy

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Transendocardial Autologous Bone Marrow Mononuclear Cell Injection in Ischemic Heart Failure

Author(s) -

Hans Fernando Rocha Dohmann,

Emerson C. Perin,

Christina Maeda Takiya,

Guilherme V. Silva,

Suzana A. Silva,

A Sousa,

Cláudio Tinoco Mesquita,

Maria-Isabel D. Rossi,

Bernardo M.O. Pascarelli,

Isabella Mariana de Assis,

Hélio S. Dutra,

João A.R. Assad,

Rodrigo V. Castello-Branco,

Cantidio Drummond,

Hans J.F. Dohmann,

James T. Willerson,

Radovan Borojević

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.499178

Subject(s) - medicine , interventricular septum , adventitia , pathology , bone marrow , angiogenesis , cell therapy , heart failure , myocyte , perfusion , cardiology , cell , ventricle , genetics , biology

Cell-based therapies for treatment of ischemic heart disease are currently under investigation. We previously reported the results of a phase I trial of transendocardial injection of autologous bone marrow mononuclear (ABMM) cells in patients with end-stage ischemic heart disease. The current report focuses on postmortem cardiac findings from one of the treated patients, who died 11 months after cell therapy.

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