Increased Susceptibility to Pulmonary Hypertension in Heterozygous BMPR2-Mutant Mice | Zendy

Yanli Song | Zendy; John E. Jones | Zendy; Hideyuki Beppu | Zendy; John F. Keaney | Zendy; Joseph Loscalzo | Zendy; Yingyi Zhang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Increased Susceptibility to Pulmonary Hypertension in Heterozygous BMPR2-Mutant Mice

Author(s) -

Yanli Song,

John E. Jones,

Hideyuki Beppu,

John F. Keaney,

Joseph Loscalzo,

Yingyi Zhang

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.492488

Subject(s) - bmpr2 , medicine , prostacyclin , pulmonary hypertension , endocrinology , thromboxane , lung , biology , bone morphogenetic protein , platelet , biochemistry , gene

Bone morphogenetic protein receptor-2 (BMPR2)-heterozygous, mutant (BMPR2(+/-)) mice have a genetic trait similar to that of certain patients with idiopathic pulmonary arterial hypertension (IPAH). To understand the role of BMPR2 in the development of IPAH, we examined the phenotype of BMPR2(+/-) mice and their response to inflammatory stress.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research