Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness, Predicts Cardiovascular Events in Well-Functioning Older Adults
Author(s) -
Kim Sutton-Tyrrell,
Samer S. Najjar,
Robert M. Boudreau,
Lakshmi Venkitachalam,
Varant Kupelian,
Eleanor M. Simonsick,
Richard J. Havlik,
Edward G. Lakatta,
Harold A. Spurgeon,
Stephen B. Kritchevsky,
Marco Pahor,
Douglas C. Bauer,
Anne B. Newman
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.483628
Subject(s) - medicine , pulse wave velocity , cardiology , arterial stiffness , quartile , heart failure , stroke (engine) , pulse pressure , blood pressure , confidence interval , mechanical engineering , engineering
Aging results in vascular stiffening and an increase in the velocity of the pressure wave as it travels down the aorta. Increased aortic pulse wave velocity (aPWV) has been associated with mortality in clinical but not general populations. The objective of this investigation was to determine whether aPWV is associated with total and cardiovascular (CV) mortality and CV events in a community-dwelling sample of older adults.
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