Antiangiogenesis Mediates Cisplatin-Induced Peripheral Neuropathy | Zendy

Rudolf Kirchmair | Zendy; Dirk Walter | Zendy; Masaaki Ii | Zendy; Kilian Rittig | Zendy; Anne Barbara Tietz | Zendy; Toshinori Murayama | Zendy; Costanza Emanueli | Zendy; Marcy Silver | Zendy; Andrea Wecker | Zendy; Carole Amant | Zendy; Peter Schratzberger | Zendy; Youngsup Yoon | Zendy; Alberto Weber | Zendy; Eleftheria Maria Panagiotou | Zendy; Kenneth M. Rosen | Zendy; Ferdinand H. Bahlmann | Zendy; Lester S. Adelman | Zendy; David H. Weinberg | Zendy; Allan H. Ropper | Zendy; Jeffrey M. Isner | Zendy; Douglas W. Losordo | Zendy

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Antiangiogenesis Mediates Cisplatin-Induced Peripheral Neuropathy

Author(s) -

Rudolf Kirchmair,

Dirk Walter,

Masaaki Ii,

Kilian Rittig,

Anne Barbara Tietz,

Toshinori Murayama,

Costanza Emanueli,

Marcy Silver,

Andrea Wecker,

Carole Amant,

Peter Schratzberger,

Youngsup Yoon,

Alberto Weber,

Eleftheria Maria Panagiotou,

Kenneth M. Rosen,

Ferdinand H. Bahlmann,

Lester S. Adelman,

David H. Weinberg,

Allan H. Ropper,

Jeffrey M. Isner,

Douglas W. Losordo

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.470849

Subject(s) - medicine , vascularity , peripheral neuropathy , cisplatin , genetic enhancement , pathology , vascular endothelial growth factor , cancer research , chemotherapy , endocrinology , biology , gene , biochemistry , vegf receptors , diabetes mellitus

Toxic neuropathies induced by cisplatin and other chemotherapeutic agents are important clinical problems because of their high incidence, their lack of effective treatment, and the fact that neuropathy represents a dose-limiting factor for these therapies. The pathogenic basis for toxic neuropathies induced by chemotherapeutic agents has not been completely elucidated.

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