Serum Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Elevated in Acute Coronary Syndrome | Zendy

Kazutaka Hayashida | Zendy; Noriaki Kume | Zendy; Takatoshi Murase | Zendy; Manabu Minami | Zendy; Daisuke Nakagawa | Zendy; Tsukasa Inada | Zendy; Masaru Tanaka | Zendy; Akira Ueda | Zendy; Goro Kominami | Zendy; Hirofumi Kambara | Zendy; Takeshi Kimura | Zendy; Toru Kita | Zendy

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Serum Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Elevated in Acute Coronary Syndrome

Author(s) -

Kazutaka Hayashida,

Noriaki Kume,

Takatoshi Murase,

Manabu Minami,

Daisuke Nakagawa,

Tsukasa Inada,

Masaru Tanaka,

Akira Ueda,

Goro Kominami,

Hirofumi Kambara,

Takeshi Kimura,

Toru Kita

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.104.468397

Subject(s) - medicine , acute coronary syndrome , lectin , mannan binding lectin , receptor , lipoprotein , endocrinology , immunology , cholesterol , myocardial infarction

Markers of cardiac injury, including troponin-T (TnT), are used to diagnose acute coronary syndrome (ACS); however, markers for plaque instability may be more useful for diagnosing ACS at the earliest stage. Lectin-like oxidized LDL receptor-1 (LOX-1) appears to play crucial roles in the pathogenesis of atherosclerotic plaque rupture and ACS onset. LOX-1 is released in part as soluble LOX-1 (sLOX-1) by proteolytic cleavage.

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