Open AccessEndocardium Contributes to Cardiac Fat
Author(s) -
Hui Zhang,
Wenjuan Pu,
Qiaozhen Liu,
Lingjuan He,
Xiuzhen Huang,
Xueying Tian,
Libo Zhang,
Yu Nie,
Shengshou Hu,
Kathy O. Lui,
Bin Zhou
Publication year - 2016
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.115.307202
Subject(s) - endocardium , medicine , epicardial fat , myocardial infarction , heart development , adipose tissue , cardiology , biology , anatomy , gene , embryonic stem cell , genetics
Unraveling the developmental origin of cardiac fat could offer important implications for the treatment of cardiovascular disease. The recent identification of the mesothelial source of epicardial fat tissues reveals a heterogeneous origin of adipocytes in the adult heart. However, the developmental origin of adipocytes inside the heart, namely intramyocardial adipocytes, remains largely unknown.
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