Open AccessHuman Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model
Author(s) -
Johannes Riegler,
Malte Tiburcy,
Antje Ebert,
Evangeline Tzatzalos,
Uwe Raaz,
Oscar J. Abilez,
Qi Shen,
Nigel G. Kooreman,
Evgenios Neofytou,
Vincent C. Chen,
Mouer Wang,
Tim Meyer,
Philip S. Tsao,
Andrew J. Connolly,
Larry A. Couture,
Joseph Gold,
Wolfram H. Zimmermann,
Joseph C. Wu
Publication year - 2015
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.115.306985
Subject(s) - transplantation , bioluminescence imaging , cardiology , heart failure , ventricular remodeling , xenotransplantation , stem cell , heart transplantation , medicine , myocyte , myocardial infarction , ischemia , ejection fraction , biology , andrology , microbiology and biotechnology , transfection , cell culture , luciferase , genetics
Tissue engineering approaches may improve survival and functional benefits from human embryonic stem cell-derived cardiomyocyte transplantation, thereby potentially preventing dilative remodeling and progression to heart failure.
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