The Identification of Nitric Oxide as Endothelium-Derived Relaxing Factor | Zendy

Joseph Loscalzo | Zendy

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The Identification of Nitric Oxide as Endothelium-Derived Relaxing Factor

Author(s) -

Joseph Loscalzo

Publication year - 2013

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/circresaha.113.301577

Subject(s) - nitric oxide , endothelium , identification (biology) , phenotype , endothelium derived relaxing factor , natural product , nitric oxide synthase , biology , microbiology and biotechnology , chemistry , biochemistry , bioinformatics , endocrinology , gene , botany

The identification of endothelium-derived relaxing factor as nitric oxide (NO) dramatically altered the course of vascular biology, as well as other biomedical disciplines. The ubiquity of this natural product of cell metabolism and the complexity of its biochemistry provide a rich source of molecular mediators of phenotype in health and disease.

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