Subpopulation of Proepicardial Cells Is Derived From the Somatic Mesoderm in the Chick Embryo | Zendy

Jan Schlueter | Zendy; Thomas Brand | Zendy

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Subpopulation of Proepicardial Cells Is Derived From the Somatic Mesoderm in the Chick Embryo

Author(s) -

Jan Schlueter,

Thomas Brand

Publication year - 2013

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/circresaha.113.301347

Subject(s) - mesoderm , lateral plate mesoderm , biology , nodal , microbiology and biotechnology , somatic cell , germ layer , ectopic expression , fgf and mesoderm formation , transcription factor , embryo , anatomy , ectoderm , genetics , embryogenesis , embryonic stem cell , gene , induced pluripotent stem cell

The proepicardium (PE) is a transient structure forming at the venous pole of the heart and gives rise to the epicardium, fibroblasts, and smooth muscle cells. The embryological origin of the PE is presently unclear. Asymmetrical formation of the PE on the right inflow tract is a conserved feature of many vertebrate embryos, and in the chicken is under the control of fibroblast growth factor 8 and snail homolog 1.

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