Gut Microbiota Metabolism of Anthocyanin Promotes Reverse Cholesterol Transport in Mice Via Repressing miRNA-10b | Zendy

Dongliang Wang | Zendy; Min Xia | Zendy; Yan Xiao | Zendy; Dan Li | Zendy; Lei Wang | Zendy; Yuxuan Xu | Zendy; Tianru Jin | Zendy; Wenhua Ling | Zendy

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Gut Microbiota Metabolism of Anthocyanin Promotes Reverse Cholesterol Transport in Mice Via Repressing miRNA-10b

Author(s) -

Dongliang Wang,

Min Xia,

Yan Xiao,

Dan Li,

Lei Wang,

Yuxuan Xu,

Tianru Jin,

Wenhua Ling

Publication year - 2012

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/circresaha.112.266502

Subject(s) - microrna , anthocyanin , gut flora , metabolism , cholesterol , biology , reverse cholesterol transport , microbiology and biotechnology , lipid metabolism , endocrinology , biochemistry , food science , gene , lipoprotein

We and others have demonstrated that anthocyanins have antiatherogenic capability. Because intact anthocyanins are absorbed very poorly, the low level of circulating parent anthocyanins may not fully account for their beneficial effect. We found recently that protocatechuic acid (PCA), a metabolite of cyanidin-3 to 0-β-glucoside (Cy-3-G), has a remarkable antiatherogenic effect.

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