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Does APD Gradient Indicate Dispersion of Repolarization ?
Author(s) -
Raja J. Selvaraj,
Krishnakumar Nair
Publication year - 2010
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.110.224048
Subject(s) - repolarization , medicine , dispersion (optics) , cardiology , human heart , chemistry , physics , optics , electrophysiology
To the Editor:The article by Glukhov et al1 is a very important study, providing, as it does, direct measurement of action potential durations (APD) transmurally in the human heart. We commend the authors for providing the first evidence for M cells in the human heart. However, we dispute the assumption throughout the article that APD gradient is a measure of dispersion of repolarization (DOR). Gradient of …

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