Impact of Timing on the Functional Recovery Achieved With Platelet Supplementation After Treatment With Ticagrelor | Zendy

M. Urooj Zafar | Zendy; Donald A. Smith | Zendy; Usman Baber | Zendy; Samantha Sartori | Zendy; Kevin Chen | Zendy; David W. Lam | Zendy; Carlos Linares-Koloffon | Zendy; Juan Rey-Mendoza | Zendy; Gustavo Jiménez Brítez | Zendy; Ginés Escolar | Zendy; Valentı́n Fuster | Zendy; Juan J. Badimón | Zendy

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Impact of Timing on the Functional Recovery Achieved With Platelet Supplementation After Treatment With Ticagrelor

Author(s) -

M. Urooj Zafar,

Donald A. Smith,

Usman Baber,

Samantha Sartori,

Kevin Chen,

David W. Lam,

Carlos Linares-Koloffon,

Juan Rey-Mendoza,

Gustavo Jiménez Brítez,

Ginés Escolar,

Valentı́n Fuster,

Juan J. Badimón

Publication year - 2017

Publication title -

circulation cardiovascular interventions

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.621

H-Index - 95

eISSN - 1941-7632

pISSN - 1941-7640

DOI - 10.1161/circinterventions.117.005120

Subject(s) - ticagrelor , medicine , aspirin , platelet , dosing , maintenance dose , loading dose , acute coronary syndrome , platelet transfusion , maintenance therapy , anesthesia , clopidogrel , cardiology , myocardial infarction , chemotherapy

American College of Cardiology/American Heart Association guidelines advise waiting 5 to 7 days before operating on P2Y 12 inhibitor-treated acute coronary syndrome patients, to allow dissipation of its antiplatelet effects. Platelet transfusion is often used to restore hemostasis during operations, but its effectiveness and optimal timing are unclear. We investigated the degree of functional gains obtained from platelet supplementation after loading and maintenance of dual antiplatelet therapy with ticagrelor and the influence of timing on this strategy.

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