Open AccessPharmacokinetics of Sirolimus-Eluting Stents Implanted in the Neonatal Arterial Duct
Author(s) -
KyongJin Lee,
Winnie Seto,
Lee Benson,
Rajiv Chaturvedi
Publication year - 2015
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.114.002233
Subject(s) - sirolimus , medicine , pharmacokinetics , stent , urology
Sirolimus-eluting stents may have clinical advantages over bare-metal stents in the extremely proliferative environment of the neonatal arterial duct. However, sirolimus has immunosuppressive actions and little is known regarding sirolimus pharmacokinetics in the newborn.
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