Prevention of Neointimal Formation After Angioplasty Using Nuclear Factor-κB Decoy Oligodeoxynucleotide-Coated Balloon Catheter in Rabbit Model | Zendy

Takashi Miyake | Zendy; Shinya Ihara | Zendy; Tetsuo Miyake | Zendy; Yusuke Tsukada | Zendy; Hajime Watanabe | Zendy; Hiroaki Matsuda | Zendy; Hideki Kiguchi | Zendy; Hiroyuki Tsujimoto | Zendy; Hironori Nakagami | Zendy; Ryuichi Morishita | Zendy

Open Access

Prevention of Neointimal Formation After Angioplasty Using Nuclear Factor-κB Decoy Oligodeoxynucleotide-Coated Balloon Catheter in Rabbit Model

Author(s) -

Takashi Miyake,

Shinya Ihara,

Tetsuo Miyake,

Yusuke Tsukada,

Hajime Watanabe,

Hiroaki Matsuda,

Hideki Kiguchi,

Hiroyuki Tsujimoto,

Hironori Nakagami,

Ryuichi Morishita

Publication year - 2014

Publication title -

circulation cardiovascular interventions

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.621

H-Index - 95

eISSN - 1941-7632

pISSN - 1941-7640

DOI - 10.1161/circinterventions.114.001522

Subject(s) - neointima , restenosis , decoy , angioplasty , balloon catheter , medicine , cancer research , balloon , stent , receptor

Despite the advent of drug-eluting stents, restenosis after endovascular intervention is still a major limitation in the treatment of cardiovascular disease. To regulate the multiple biological mechanisms underlying restenosis, we focused on inhibition of an important transcription factor, nuclear factor-kappaB (NFκB), using a decoy strategy.

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