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Fully Integrated High-Speed Intravascular Optical Coherence Tomography/Near-Infrared Fluorescence Structural/Molecular Imaging In Vivo Using a Clinically Available Near-Infrared Fluorescence–Emitting Indocyanine Green to Detect Inflamed Lipid-Rich Atheromata in Coronary-Sized Vessels
Author(s) -
Sunki Lee,
Min Woo Lee,
Han Saem Cho,
Joon Woo Song,
Hyeong Soo Nam,
Dong Joo Oh,
Kyeongsoon Park,
WangYuhl Oh,
Hongki Yoo,
Jin Won Kim
Publication year - 2014
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.114.001498
Subject(s) - optical coherence tomography , medicine , indocyanine green , fluorescence , fluorescence lifetime imaging microscopy , preclinical imaging , molecular imaging , infrared , in vivo , vulnerable plaque , biomedical engineering , optics , radiology , pathology , physics , microbiology and biotechnology , biology
Lipid-rich inflamed coronary plaques are prone to rupture. The purpose of this study was to assess lipid-rich inflamed plaques in vivo using fully integrated high-speed optical coherence tomography (OCT)/near-infrared fluorescence (NIRF) molecular imaging with a Food and Drug Administration-approved indocyanine green (ICG).

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