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Randomized Comparison Between Polymer-Free Versus Polymer-Based Paclitaxel-Eluting Stent
Author(s) -
Yoshitaka Shiratori,
Clarissa Cola,
Salvatore Brugaletta,
Luis Álvarez-Contreras,
Victoria MartínYuste,
Bruno García del Blanco,
Rafael Ruíz-Salmerón,
José Francisco Díaz Fernández,
Eduardo Pinar,
Vicens Martı́,
Juan García-Picart,
Manel Sabaté
Publication year - 2014
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.113.000800
Subject(s) - medicine , stent , intravascular ultrasound , percutaneous coronary intervention , myocardial infarction , revascularization , clinical endpoint , randomized controlled trial , paclitaxel , drug eluting stent , surgery , urology , chemotherapy
Most drug-eluting stents currently in use are coated with a polymer carrying the drug that is released for several weeks. However, a durable polymer may provoke hypersensitive reaction, delayed artery healing, and eventually stent thrombosis. The aim of this study was to investigate the safety and efficacy of a polymer-free paclitaxel-eluting stent (PF-PES) versus a polymer-based PES (PB-PES).

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