End-Diastolic Fractional Flow Reserve
Author(s) -
David Chalyan,
Zhang Zhang,
Shigeho Takarada,
Sabee Molloi
Publication year - 2014
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.113.000327
Subject(s) - fractional flow reserve , diastole , cardiology , medicine , circumflex , artery , blood pressure , coronary angiography , myocardial infarction
Diastolic fractional flow reserve (dFFR) has been shown to be highly sensitive for detection of inducible myocardial ischemia. However, its reliance on measurement of left-ventricular pressure for zero-flow pressure correction, as well as manual extraction of the diastolic interval, has been its major limitation. Given previous reports of minimal zero-flow pressure at end-diastole, we compared instantaneous ECG-gated end-diastolic FFR with conventional full-cardiac cycle FFR and other diastolic indices in the porcine model.
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