Stent Revascularization Restores Cortical Blood Flow and Reverses Tissue Hypoxia in Atherosclerotic Renal Artery Stenosis but Fails to Reverse Inflammatory Pathways or Glomerular Filtration Rate
Author(s) -
Ahmed Saad,
Sandra M. Herrmann,
John A. Crane,
James F. Glockner,
Michael A. McKusick,
Sanjay Misra,
Alfonso Eirin,
Behzad Ebrahimi,
Lilach O. Lerman,
Stephen C. Textor
Publication year - 2013
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.113.000219
Subject(s) - medicine , renal blood flow , renal function , revascularization , kidney , renal circulation , renal artery stenosis , urology , cardiology , endocrinology , renal artery , myocardial infarction
Atherosclerotic renal artery stenosis (ARAS) is known to reduce renal blood flow, glomerular filtration rate (GFR) and amplify kidney hypoxia, but the relationships between these factors and tubulointerstitial injury in the poststenotic kidney are poorly understood. The purpose of this study was to examine the effect of renal revascularization in ARAS on renal tissue hypoxia and renal injury.
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