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Influence of the Amount of Myocardium Subtended by a Stenosis on Fractional Flow Reserve
Author(s) -
Antonio Maria Leone,
Alberto Ranieri De Caterina,
Eloisa Basile,
Andrea Gardi,
Domenico Laezza,
Mario Attilio Mazzari,
Rocco Mongiardo,
Rajesh Kharbanda,
Florim Cuculi,
Italo Porto,
Giampaolo Niccoli,
Francesco Burzotta,
Carlo Trani,
Adrian Banning,
Antonio G. Rebuzzi,
Filippo Crea
Publication year - 2013
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.112.971101
Subject(s) - fractional flow reserve , medicine , cardiology , stenosis , circumflex , lumen (anatomy) , occlusion , coronary artery disease , lesion , coronary angiography , myocardial infarction , artery , surgery
Fractional flow reserve (FFR) specifically relates to the severity of a stenosis to the mass of tissue to be perfused. Accordingly, the larger the territory to be perfused, the greater the flow and the pressure gradient induced by maximal hyperemia. Although this notion may be considered intuitive, its unequivocal demonstration is still lacking. The aim of our study was to evaluate the influence of the amount of myocardium subtended to an intermediate stenosis on FFR, especially in relation to quantitative coronary angiography.

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