Vasodilatory Capacity of the Coronary Microcirculation is Preserved in Selected Patients With Non–ST-Segment–Elevation Myocardial Infarction
Author(s) -
Jamie Layland,
David Carrick,
Margaret McEntegart,
Nadeem Ahmed,
Alex Payne,
John McClure,
Arvind Sood,
Ross McGeoch,
Andrew I. MacIsaac,
Robert Whitbourn,
Andrew Wilson,
Keith G. Oldroyd,
Colin Berry
Publication year - 2013
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.112.000180
Subject(s) - medicine , cardiology , fractional flow reserve , culprit , coronary flow reserve , myocardial infarction , percutaneous coronary intervention , microcirculation , coronary circulation , coronary artery disease , blood flow , coronary angiography
The use of fractional flow reserve in patients with non-ST-segment-elevation myocardial infarction (NSTEMI) is a controversial issue. We undertook a study to assess the vasodilatory capacity of the coronary microcirculation in patients with NSTEMI when compared with a model of preserved microcirculation (stable angina [SA] cohort: culprit and nonculprit vessel) and acute microcirculatory dysfunction (ST-segment-elevation myocardial infarction [STEMI] cohort). We hypothesized that the vasodilatory response of the microcirculation would be preserved in NSTEMI.
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