Randomized Comparison of Sirolimus-Eluting and Everolimus-Eluting Coronary Stents in the Treatment of Total Coronary Occlusions
Author(s) -
Raúl Moreno,
Eulogio Garcı́a,
Rui Campante Teles,
José Ramón Rumoroso,
Henrique Carvalho,
Francisco Javier Goicolea,
José Moreu,
Josefa Mauri,
Manel Sabaté,
Vicente Mainar,
Lino Patrício,
Mariano Valdés,
Felipez Fernández Vázquez,
Ángel SánchezRecalde,
Guillermo Galeote,
Santiago JiménezValero,
Manuel Almeida,
Esteban López de Sá,
Luís Calvo,
Ignacio Plaza,
J L López-Sendón,
Jose-Luis R. Martín
Publication year - 2013
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.112.000076
Subject(s) - medicine , sirolimus , stent , everolimus , restenosis , cardiology , clinical endpoint , randomized controlled trial , surgery
Patients with coronary total occlusions are at especially high risk for restenosis and new revascularizations. Sirolimus-eluting stents dramatically improved the clinical outcome of this subset of patients in randomized trials, but other drug-eluting stents, mainly the everolimus-eluting stent (currently the most frequently used stent), have not yet been evaluated in patients with coronary total occlusions. The objective was to compare the second-generation everolimus-eluting stent with the first-generation sirolimus-eluting stent in patients with coronary total occlusions.
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