Impact of Parallel Micro-Engineered Stent Grooves on Endothelial Cell Migration, Proliferation, and Function | Zendy

Eugene A. Sprague | Zendy; Fermin O. Tio | Zendy; Sophia Ahmed | Zendy; Juan F. Granada | Zendy; Steven R. Bailey | Zendy

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Impact of Parallel Micro-Engineered Stent Grooves on Endothelial Cell Migration, Proliferation, and Function

Author(s) -

Eugene A. Sprague,

Fermin O. Tio,

Sophia Ahmed,

Juan F. Granada,

Steven R. Bailey

Publication year - 2012

Publication title -

circulation cardiovascular interventions

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.621

H-Index - 95

eISSN - 1941-7632

pISSN - 1941-7640

DOI - 10.1161/circinterventions.111.967901

Subject(s) - restenosis , stent , nitric oxide , apoptosis , endothelial stem cell , biocompatibility , endothelium , coronary arteries , cell growth , medicine , artery , in vitro , chemistry , biomedical engineering , cardiology , biochemistry , organic chemistry

Stent luminal surface characteristics influence surface endothelialization. We hypothesize that luminal stent microgrooves created in the direction of coronary flow accelerate endothelial cell migration, resulting in lower levels of neointimal formation.

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