Open AccessRanolazine Injection Into Coronary or Femoral Arteries Exerts Marked, Transient Regional Vasodilation Without Systemic Hypotension in an Intact Porcine Model
Author(s) -
Tuomo Nieminen,
Caio A.M. Tavares,
José Roberto Mendes Pegler,
Luiz Belardinelli,
Richard L. Verrier
Publication year - 2011
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.111.962852
Subject(s) - ranolazine , medicine , prazosin , femoral artery , vasodilation , cardiology , artery , vascular resistance , blood pressure , hemodynamics , mean arterial pressure , anesthesia , aortic pressure , heart rate , antagonist , receptor
We examined whether intracoronary or intrafemoral administration of ranolazine produces local vasodilation.
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