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Letter by Dregelid Regarding Article, “Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients With Critical Limb Ischemia: A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger Disease”
Author(s) -
Einar Dregelid
Publication year - 2011
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.111.961375
Subject(s) - medicine , amputation , critical limb ischemia , surgery , bone marrow , ischemia , peripheral blood mononuclear cell , disease , myocardial infarction , arterial disease , vascular disease , biochemistry , chemistry , in vitro
To the Editor:A main finding in the study by Idei et al1 was that patients who underwent bone marrow mononuclear cell (BM-MNC) implantation had a highly significantly higher major amputation-free survival rate than patients who did not undergo BM-MNC implantation.A major amputation is not a spontaneous event such as stroke or myocardial infarction. Before reaching a decision concerning amputation, there is interaction between the patient and a surgeon. A surgeon nonblinded to type of treatment may have been more prone to recommend amputation in control patients …

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