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Paclitaxel-Eluting Stents Compared With Bare Metal Stents in Diabetic Patients With Acute Myocardial Infarction
Author(s) -
Bernhard Witzenbichler,
Jochen Wöhrle,
Giulio Guagliumi,
Jan Z. Peruga,
Bruce R. Brodie,
Dariusz Dudek,
Ran Kornowski,
Franz Hartmann,
Kristin L. Hood,
Helen Parise,
Alexandra J. Lansky,
Eugenia Nikolsky,
Roxana Mehran,
Gregg W. Stone
Publication year - 2011
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.110.960245
Subject(s) - medicine , hazard ratio , myocardial infarction , cardiology , percutaneous coronary intervention , diabetes mellitus , confidence interval , stent , revascularization , surgery , endocrinology
In the prospective, randomized Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial, implantation of paclitaxel-eluting stents (PES) safely reduced the rates of ischemic target lesion revascularization (TLR) compared with bare metal stents (BMS) in patients with ST-segment-elevation myocardial infarction (STEMI) undergoing primary percutaneous intervention. Diabetes mellitus is a known predictor of adverse outcomes after percutaneous intervention in STEMI. We therefore sought to assess the impact of PES in diabetic patients with STEMI from the HORIZONS-AMI trial.

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