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Clinical Outcomes in Patients With the Concomitant Use of Clopidogrel and Proton Pump Inhibitors After Percutaneous Coronary Intervention
Author(s) -
Kishore J. Harjai,
Chetan Shenoy,
Pam Orshaw,
Samer Usmani,
Judy Boura,
Rajendra H. Mehta
Publication year - 2011
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.110.958884
Subject(s) - medicine , mace , percutaneous coronary intervention , clopidogrel , myocardial infarction , conventional pci , cardiology , coronary artery disease , concomitant , revascularization , thienopyridine , propensity score matching , angioplasty
The concomitant use of proton pump inhibitors (PPIs) with clopidogrel is suspected to be associated with an adverse impact on clinical outcomes in patients with coronary artery disease. We sought to evaluate whether the use of PPIs with clopidogrel was associated with worse clinical outcomes after percutaneous coronary intervention (PCI) compared with the use of clopidogrel alone.

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