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Impact of Femoral Vascular Closure Devices and Antithrombotic Therapy on Access Site Bleeding in Acute Coronary Syndromes
Author(s) -
Timothy A. Sanborn,
Ramin Ebrahimi,
Steven V. Manoukian,
Brent McLaurin,
David A. Cox,
Frederick Feit,
Martial Hamon,
Roxana Mehran,
Gregg W. Stone
Publication year - 2010
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.109.896704
Subject(s) - bivalirudin , medicine , vascular closure device , percutaneous coronary intervention , antithrombotic , acute coronary syndrome , odds ratio , hematoma , surgery , femoral artery , cardiology , myocardial infarction
The Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial demonstrated that bivalirudin monotherapy significantly reduces major bleeding compared with heparin (unfractionated or enoxaparin) or bivalirudin plus a glycoprotein IIb/IIIa inhibitor in acute coronary syndromes. Whether vascular closure devices (VCD) impact these results is unknown. Therefore, this study sought to determine whether VCD impact major access site bleeding (ASB) in patients with acute coronary syndromes undergoing early invasive management by the femoral approach.

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