A Comparison of Abciximab and Small-Molecule Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Primary Percutaneous Coronary Intervention
Author(s) -
Hitinder S. Gurm,
Umesh Tamhane,
Pascal Meier,
Paul Grossman,
Stanley Chetcuti,
Eric Bates
Publication year - 2009
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.108.847996
Subject(s) - abciximab , eptifibatide , medicine , tirofiban , percutaneous coronary intervention , myocardial infarction , cardiology , odds ratio , randomized controlled trial
Current guidelines recommend abciximab as the preferred agent for patients undergoing primary percutaneous coronary intervention, yet small-molecule glycoprotein IIb/IIIa inhibitors are more commonly used in clinical practice. The objective of our meta-analysis was to evaluate for differences in clinical outcome between small-molecule glycoprotein IIb/IIIa inhibitors and abciximab in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
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