Drug-Eluting Stents Versus Bare-Metal Stents for Off-Label Indications
Author(s) -
David Austin,
Keith G. Oldroyd,
Alex McConnachie,
Rachel D. Slack,
Hany Eteiba,
Andrew D. Flapan,
Kevin Jennings,
Robin J. Northcote,
A C H Pell,
Ian R. Starkey,
Jill P. Pell
Publication year - 2008
Publication title -
circulation cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.621
H-Index - 95
eISSN - 1941-7632
pISSN - 1941-7640
DOI - 10.1161/circinterventions.108.769042
Subject(s) - bare metal , medicine , off label use , drug , stent , radiology , restenosis , pharmacology
The US Food and Drug Administration recently concluded that data on off-label drug-eluting stent (DES) safety are limited. However, in actual clinical practice, DES are often used for off-label indications, and observational studies demonstrate that complications are higher when compared with on-label use. We aimed to determine whether clinical outcomes differ after DES and bare-metal stent implantation in a patient cohort defined by DES off-label indications.
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