Tale of 2 Orifices

January 2019 1 Alan F. Vainrib, MD Didier F. Loulmet, MD Mathew R. Williams, MD Muhamed Saric, MD, PhD Because the congenital double-orifice mitral valve (DOMV) was first reported by William Smith Greenfield in 1876, there have been multiple forms described in the literature.1 DOMV can be divided into 4 subtypes based on cause: 2 native forms (congenital native and acquired native) and 2 iatrogenic forms (surgical and percutaneous). These subtypes have remarkably similar appearances on 2-dimensional (2D) and 3-dimensional (3D) echocardiography. We describe the historical background and 3D echocardiographic imaging of these various types of DOMV.