Open AccessAbsence of Myocardial Fibrosis Predicts Favorable Long-Term Survival in New-Onset Heart Failure
Author(s) -
Ankur Gulati,
Alan G. Japp,
Sadaf Raza,
Brian P. Halliday,
Daniel A. Jones,
Simon Newsome,
Nizar Ismail,
Kishen Morarji,
Jahanzaib Khwaja,
Nick Spath,
Carl Shakespeare,
Paul R. Kalra,
Guy Lloyd,
Anthony Mathur,
John G.F. Cleland,
Martín Cowie,
Ravi Assomull,
Dudley J. Pennell,
Tevfik F. Ismail,
Sanjay Prasad
Publication year - 2018
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.118.007722
Subject(s) - medicine , fibrosis , ejection fraction , cardiology , hazard ratio , myocardial fibrosis , heart failure , myocardial infarction , cardiac fibrosis , sudden cardiac death , sudden death , confidence interval
The pattern and extent of myocardial fibrosis predict adverse outcomes in new-onset HF and reduced LVEF. In contrast, the absence of fibrosis portends a durable warranty period with a low incidence of adverse events. These findings support a role for late gadolinium enhancement cardiovascular magnetic resonance in the early risk stratification of patients with HF of uncertain pathogenesis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom