Mitral Leaflet Changes Following Myocardial Infarction
Author(s) -
Jonathan Beaudoin,
Jacob P. DalBianco,
Elena Aïkawa,
Joyce Bischoff,
Jorge Guerrero,
Suzanne Sullivan,
Philipp E. Bartko,
Mark D. Handschumacher,
DaeHee Kim,
Jill WylieSears,
Jacob Aaron,
Robert A. Levine
Publication year - 2017
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.117.006512
Subject(s) - medicine , cardiology , myocardial infarction , fibrosis , thickening , leaflet (botany) , mitral valve , infarction , paleontology , chemistry , polymer science , biology
Ischemic mitral regurgitation (MR) is classically ascribed to functional restriction of normal leaflets, but recent studies have suggested post-myocardial infarction (MI) mitral valve (MV) leaflet fibrosis and thickening, challenging valve normality. Progression of leaflet thickness post-MI has not been studied. We hypothesized that excessive MV remodeling post-MI contributes to MR. Our objectives are to characterize MV changes after MI and relate them to MR.
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