Lowering Interleukin-12 Activity Improves Myocardial and Vascular Function Compared With Tumor Necrosis Factor-a Antagonism or Cyclosporine in Psoriasis | Zendy

Ignatios Ikonomidis | Zendy; Evangelia Papadavid | Zendy; George Makavos | Zendy; Ioanna Andreadou | Zendy; Maria Varoudi | Zendy; Kostas Gravanis | Zendy; Konstantinos Theodoropoulos | Zendy; George Pavlidis | Zendy; Helen Triantafyllidi | Zendy; Paraskevi Moutsatsou | Zendy; Christina Panagiotou | Zendy; John Parissis | Zendy; Efstathios K. Iliodromitis | Zendy; John Lekakis | Zendy; Dimitrios Rigopoulos | Zendy

Open Access

Lowering Interleukin-12 Activity Improves Myocardial and Vascular Function Compared With Tumor Necrosis Factor-a Antagonism or Cyclosporine in Psoriasis

Author(s) -

Ignatios Ikonomidis,

Evangelia Papadavid,

George Makavos,

Ioanna Andreadou,

Maria Varoudi,

Kostas Gravanis,

Konstantinos Theodoropoulos,

George Pavlidis,

Helen Triantafyllidi,

Paraskevi Moutsatsou,

Christina Panagiotou,

John Parissis,

Efstathios K. Iliodromitis,

John Lekakis,

Dimitrios Rigopoulos

Publication year - 2017

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.117.006283

Subject(s) - medicine , antagonism , psoriasis , tumor necrosis factor alpha , tumor necrosis factor α , interleukin , necrosis , cytokine , cardiology , pathology , immunology , receptor

Interleukin (IL)-12 activity is involved in the pathogenesis of psoriasis and acute coronary syndromes. We investigated the effects of IL-12 inhibition on vascular and left ventricular (LV) function in psoriasis.

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