Disease Stage–Dependent Changes in Cardiac Contractile Performance and Oxygen Utilization Underlie Reduced Myocardial Efficiency in Human Inherited Hypertrophic Cardiomyopathy | Zendy

Ahmet Güçlü | Zendy; Paul Knaapen | Zendy; Hendrik J. Harms | Zendy; Rahana Y. Parbhudayal | Zendy; Michelle Michels | Zendy; Adriaan A. Lammertsma | Zendy; Albert C. van Rossum | Zendy; Tjeerd Germans | Zendy; Jolanda van der Velden | Zendy

Open Access

Disease Stage–Dependent Changes in Cardiac Contractile Performance and Oxygen Utilization Underlie Reduced Myocardial Efficiency in Human Inherited Hypertrophic Cardiomyopathy

Author(s) -

Ahmet Güçlü,

Paul Knaapen,

Hendrik J. Harms,

Rahana Y. Parbhudayal,

Michelle Michels,

Adriaan A. Lammertsma,

Albert C. van Rossum,

Tjeerd Germans,

Jolanda van der Velden

Publication year - 2017

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.116.005604

Subject(s) - medicine , hypertrophic cardiomyopathy , cardiology , cardiomyopathy , disease , stage (stratigraphy) , heart failure , paleontology , biology

Reduced myocardial efficiency represents a target for therapy in hypertrophic cardiomyopathy although therapeutic benefit may depend on disease stage. Here, we determined disease stage-dependent changes in myocardial efficiency and effects of myectomy surgery.

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