Comparison of Fractional Flow Reserve Assessment With Demand Stress Myocardial Contrast Echocardiography in Angiographically Intermediate Coronary Stenoses | Zendy

Juefei Wu | Zendy; David Barton | Zendy; Feng Xie | Zendy; Edward O’Leary | Zendy; John Steuter | Zendy; Gregory Pavlides | Zendy; Thomas R. Porter | Zendy

Open Access

Comparison of Fractional Flow Reserve Assessment With Demand Stress Myocardial Contrast Echocardiography in Angiographically Intermediate Coronary Stenoses

Author(s) -

Juefei Wu,

David Barton,

Feng Xie,

Edward O’Leary,

John Steuter,

Gregory Pavlides,

Thomas R. Porter

Publication year - 2016

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.116.004129

Subject(s) - medicine , cardiology , fractional flow reserve , dobutamine , stress echocardiography , perfusion , stenosis , coronary artery disease , hemodynamics , coronary circulation , blood flow , coronary angiography , myocardial infarction

Real-time myocardial contrast echocardiography (RTMCE) directly measures capillary flow (CBF), which in turn is a major regulator of coronary flow and resistance during demand or hyperemic stress. Although fractional flow reserve (FFR) was developed to assess the physiological relevance of an epicardial stenosis, it assumes maximal microvascular vasodilation and minimal resistance during vasodilator stress. Therefore, we sought to determine the relationship between CBF assessed with RTMCE during stress echocardiography and FFR in intermediate coronary lesions.

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