Cardiac Involvement in Myotonic Dystrophy Type 2 Patients With Preserved Ejection Fraction | Zendy

Luisa Schmacht | Zendy; Julius Traber | Zendy; Ulrike Grieben | Zendy; Wolfgang Utz | Zendy; Matthias A. Dieringer | Zendy; Peter Kellman | Zendy; Edyta Błaszczyk | Zendy; Florian von KnobelsdorffBrenkenhoff | Zendy; Simone Spuler | Zendy; Jeanette SchulzMenger | Zendy

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Cardiac Involvement in Myotonic Dystrophy Type 2 Patients With Preserved Ejection Fraction

Author(s) -

Luisa Schmacht,

Julius Traber,

Ulrike Grieben,

Wolfgang Utz,

Matthias A. Dieringer,

Peter Kellman,

Edyta Błaszczyk,

Florian von KnobelsdorffBrenkenhoff,

Simone Spuler,

Jeanette SchulzMenger

Publication year - 2016

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.115.004615

Subject(s) - myotonic dystrophy , ejection fraction , cardiology , fraction (chemistry) , medicine , heart failure , chemistry , organic chemistry

Myotonic dystrophy type 2 (DM2) is a genetic disorder characterized by skeletal muscle symptoms, metabolic changes, and cardiac involvement. Histopathologic alterations of the skeletal muscle include fibrosis and fatty infiltration. The aim of this study was to investigate whether subclinical cardiac involvement in DM2 is already detectable in preserved left ventricular function by cardiovascular magnetic resonance.

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