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Association of Central Adiposity With Adverse Cardiac Mechanics
Author(s) -
Senthil Selvaraj,
Eva E. Martinez,
Frank G. Aguilar,
KwangYoun A. Kim,
Jie Peng,
Jin Sha,
Marguerite R. Irvin,
Cora E. Lewis,
Steven C. Hunt,
Donna K. Arnett,
Sanjiv J. Shah
Publication year - 2016
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.115.004396
Subject(s) - medicine , waist , cardiology , body mass index , ejection fraction , blood pressure , diastole , population , obesity , heart failure , environmental health
Central obesity, defined by increased waist circumference or waist:hip ratio (WHR), is associated with increased cardiovascular events, including heart failure. However, the pathophysiological link between central obesity and adverse cardiovascular outcomes remains poorly understood. We hypothesized that central obesity and larger WHR are independently associated with worse cardiac mechanics (reduced left ventricular strain and systolic [s'] and early diastolic [e'] tissue velocities).

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