Prognostic Utility and Clinical Significance of Cardiac Mechanics in Heart Failure With Preserved Ejection Fraction | Zendy

Benjamin H. Freed | Zendy; Vistasp Daruwalla | Zendy; Jeanette Cheng | Zendy; Frank G. Aguilar | Zendy; Lauren BeussinkNelson | Zendy; Andrew D. Choi | Zendy; David A. Klein | Zendy; Debra Dixon | Zendy; Abigail S. Baldridge | Zendy; Laura J. RasmussenTorvik | Zendy; Kameswari Maganti | Zendy; Sanjiv J. Shah | Zendy

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Prognostic Utility and Clinical Significance of Cardiac Mechanics in Heart Failure With Preserved Ejection Fraction

Author(s) -

Benjamin H. Freed,

Vistasp Daruwalla,

Jeanette Cheng,

Frank G. Aguilar,

Lauren BeussinkNelson,

Andrew D. Choi,

David A. Klein,

Debra Dixon,

Abigail S. Baldridge,

Laura J. RasmussenTorvik,

Kameswari Maganti,

Sanjiv J. Shah

Publication year - 2016

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.115.003754

Subject(s) - cardiology , medicine , ejection fraction , heart failure , speckle tracking echocardiography , atrial fibrillation , hazard ratio , heart failure with preserved ejection fraction , confidence interval

Left atrial (LA) enlargement is associated with adverse events in heart failure with preserved ejection fraction (HFpEF). However, the role of LA mechanics (ie, LA strain measures) in HFpEF has not been well studied. We hypothesized that in HFpEF, reduced (worse) LA strain is a key pathophysiologic abnormality and is a stronger correlate of adverse events than left ventricular or right ventricular longitudinal strain.

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