Augmentation of Limb Perfusion and Reversal of Tissue Ischemia Produced by Ultrasound-Mediated Microbubble Cavitation | Zendy

J. Todd Belcik | Zendy; Brian Mott | Zendy; Aris Xie | Zendy; Yan Zhao | Zendy; Sajeevani Kim | Zendy; Nathan J. Lindner | Zendy; Azzdine Y. Ammi | Zendy; Joel Linden | Zendy; Jonathan R. Lindner | Zendy

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Augmentation of Limb Perfusion and Reversal of Tissue Ischemia Produced by Ultrasound-Mediated Microbubble Cavitation

Author(s) -

J. Todd Belcik,

Brian Mott,

Aris Xie,

Yan Zhao,

Sajeevani Kim,

Nathan J. Lindner,

Azzdine Y. Ammi,

Joel Linden,

Jonathan R. Lindner

Publication year - 2015

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.114.002979

Subject(s) - microbubbles , ultrasound , medicine , perfusion , mechanical index , hindlimb , femoral artery , limb perfusion , blood flow , vasodilation , ischemia , nitric oxide , cardiology , anatomy , radiology

Ultrasound can increase tissue blood flow, in part, through the intravascular shear produced by oscillatory pressure fluctuations. We hypothesized that ultrasound-mediated increases in perfusion can be augmented by microbubble contrast agents that undergo ultrasound-mediated cavitation and sought to characterize the biological mediators.

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